Search found 21 matches

by professoreden
Wed Oct 23, 2019 3:54 pm
Forum: PSA and other markers
Topic: Biochemical Recurrence
Replies: 2
Views: 3579

Re: Biochemical Recurrence

Chris, you need to be referred to an Oncologist rather than a Urologist. They are likely to request a PET CT scan to determine to site of your PSA generation to look to see if it can be specifically targeted. You have been unlucky, but your tumour was locally advanced (T3) at the time of surgery, wh...
by professoreden
Tue Jul 11, 2017 7:39 pm
Forum: PSA and other markers
Topic: PSA Increase
Replies: 1
Views: 3625

Re: PSA Increase

Chris I can see how the change in numbers is unsettling for you. The fact that your PSA has both apparently fallen and risen following surgery highlights the fact that the PSA test is not very accurate at the lowest limit of detection. This is why the definition of biochemical recurrence (failure) i...
by professoreden
Sat Jul 16, 2016 1:26 pm
Forum: Interpreting results
Topic: Testosterone
Replies: 1
Views: 5666

Re: Testosterone

Roland It is certainly possible that your low testosterone is contributing towards your erectile dysfunction (ED) and now that you are more than 1 year following surgery it would be reasonable to start testosterone replacement therapy. This is usually in the form of a gel or a patch applied to the s...
by professoreden
Tue Jul 05, 2016 9:25 pm
Forum: Biopsy
Topic: Biopsy result accuracy
Replies: 1
Views: 5004

Re: Biopsy result accuracy

Carlos A biopsy is only a sample and, as you point out, can be inaccurate if it fails to represent the whole organ. This is called sampling error. The larger the prostate, the greater the possibility of sampling error (think needle and haystack). Sampling error can be reduced in a number of ways: ta...
by professoreden
Tue Jul 05, 2016 9:19 pm
Forum: Surgery
Topic: Da Vinci
Replies: 1
Views: 5007

Re: Da Vinci

Carlos This is an excellent question and the short answer is that it depends on the surgeon. Excellent results have been published in the medical literature for open, laparoscopic and robotic surgery, but so have very poor results and, by definition, most surgeons will achieve average results using ...
by professoreden
Wed Jun 01, 2016 11:54 am
Forum: PSA and other markers
Topic: What Does PSA Count 0.08 Actually Mean in My Case?
Replies: 1
Views: 9236

Re: What Does PSA Count 0.08 Actually Mean in My Case?

Chris Unfortunately, up-staging and up-grading of prostate cancer, as was seen in your case, is not rare and occurs in 5-30% of men, depending on which surgical series from the published literature you read. The advantage of surgery over radiotherapy as the initial treatment is that armed with knowl...
by professoreden
Wed May 25, 2016 11:41 am
Forum: Recurrence and salvage options
Topic: Recurrence in lymph nodes after prostatectomy
Replies: 1
Views: 5905

Re: Recurrence in lymph nodes after prostatectomy

Hi and I'm sorry to read about your father's problem. I assume that you meant 6 month (rather than 6 week) check as November 2015 was 6 months ago and that he's had some form of imaging that shows nodal recurrence, such as a CT, MRI or PET CT scan, which followed an elevated PSA level. Depending on ...
by professoreden
Wed May 25, 2016 11:12 am
Forum: Active surveillance
Topic: When to give up on active surveillance
Replies: 1
Views: 5056

Re: When to give up on active surveillance

Peter The 3 scenarios that commonly cause men to abandon active surveillance and seek definitive treatment are:- PSA progression. Gleason progression. Wanting to end uncertainty. If I understand your post correctly, your PSA in 2012 was 5.7 and is still 5.7 in 2016 but has fluctuated significantly b...
by professoreden
Fri May 06, 2016 9:56 pm
Forum: Choosing a treatment
Topic: Elevated PSA and 4K Scores
Replies: 1
Views: 17421

Re: Elevated PSA and 4K Scores

Hi. I think that many of the answers to your questions are covered in http://www.theprostateclinic.org/community/viewtopic.php?f=5&t=803 . Total PSA is elevated by age, prostate size, prostate injury (such as biopsy), urinary infection, bladder outlet obstruction and ejaculation, as well as canc...
by professoreden
Fri May 06, 2016 9:38 pm
Forum: MRI and other scans
Topic: Biopsy Procedural Differences in the States
Replies: 1
Views: 12424

Re: Biopsy Procedural Differences in the States

PSA is an imperfect tumour marker but it is still an excellent tool for identifying men in whom more interest needs to be taken to either exclude or confirm the presence of prostate cancer. We know this because the largest screening study for prostate cancer (the European Randomised Screening study ...

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